Sir Michael is Chairman of the Medicines and Healthcare products Regulatory Agency (since December 2014). He is a Clinical Phamacologist and Specialist in Internal Medicine. He was Professor of Clinical Pharmacology in Newcastle, and Physician at the Newcastle Hospitals, from 1999-2006.

He was Chairman of the Committee on Safety of Medicines (1992-1998), Chairman of the Advisory Council on the Misuse of Drugs (1998-2008) and founding Chairman of the National Institute for Clinical Excellence (1999-2013). He is recent past President of the Royal Society of Medicine (2012-2014).

Currently Sir Michael is Chairman of UK Biobank, Honorary Professor at the London School of Hygiene and Tropical Medicine, and Emeritus Professor at the University of Newcastle upon Tyne.

Sir Michael was appointed the Chairman of the Medicines and Healthcare products Regulatory Agency (MHRA) on 1st December 2014.

Dr Adam chairs one of the Technology Appraisal committees of the National Institute of Care Excellence. She is also a Consultant Radiologist at St. George’s Hospital, London, with a special interest in imaging of diseases of the ear, nose and throat. 

She is former founding Chair of the European Society of Radiology Audit and Standards Committee and currently chairs the ESR Quality, Safety and Standards Committee and is a Member of the Executive Committee. 

Dr Adam has been a member of the Council of the Royal College of Radiologists, RCR lead for revalidation and has chaired various other College committees. She has a long-standing interest in standard setting and evaluation and has lectured nationally and internationally on these subjects.

Stephen Evans is Professor of Pharmacoepidemiology at the London School of Hygiene and Tropical Medicine (LSHTM) and is a medical statistician.

Stephen was at the UK Medicines Control Agency (now the MHRA) from 1995 to 1999, and 2000-2002. While at the MCA he dealt with major safety issues such as HRT and breast cancer; vitamin K and childhood cancer; MMR and autism.

After training in Physics and Computing, he joined The London Hospital in 1970 becoming Professor of Medical Statistics in 1990.

He is or has been on various editorial boards, including the British Journal of Clinical Pharmacology and is an Associate Editor of Pharmaco-epidemiology and Drug Safety. He has been a statistical advisor to the British Medical Journal and a member of its editorial review committee for over 15 years. He is an independent expert member of the European Medicines Agency’s committee that deals with drug safety (PRAC), and was a member of the WHO Global Advisory Committee on Vaccine Safety. He is an Honorary fellow of The Royal College of Physicians of London.

Dr Raine trained in general medicine in Oxford after completing a Masters degree by research in Pharmacology.  Her interest in drug safety led to a career in medicines regulation which has spanned a number of roles in assessment, management and strategic development within the UK national authority.

Appointed in 1999 to head Pharmacovigilance in the Medicines Control Agency (now Medicines and Healthcare products Regulatory Agency), she was elected in 2005 to chair the EU Pharmacovigilance Working Party and in 2012 as the first chair of the European Medicines Agency’s Pharmacovigilance Risk Assessment Committee.  She is also a member of the WHO Advisory Committee on Safety of Medicinal Products and a board member of the International Society for Pharmacoepidemiology.

Dr Raine has a special interest in strengthening the evidence base for regulatory decision-making and she has driven forward the use of pharmacoepidemiological methodologies in pharmacovigilance, including use of the UK’s Clinical Practice Research Datalink.   Her current interests include monitoring the outcomes of regulatory action, risk communication and patient involvement in the regulatory process.

Professor Routledge is an Honorary Consultant Physician and Clinical Pharmacologist in Cardiff and Vale University Health Board, and Head of the Department of Pharmacology, Therapeutics and Toxicology in Cardiff University School of Medicine.

He has served on several MHRA regulatory committees, including the Medicines Commission UK, and on appraisal committees of NICE. He was appointed first Chairman of the newly-formed UK Herbal Medicines Advisory Committee in 2005, and from 2006 until 2014, served as Chairman of the All-Wales Medicines Strategy Group (AWMSG). He is also a member of the Bevan Commission, an impartial advisory group to the Minister for Health and Social Services (and other Welsh Government Ministers).

Professor Routledge is a President Emeritus of the British Pharmacological Society, an Honorary Fellow of the Royal College of General Practitioners, the Royal Society of Biology and the Faculty of Pharmaceutical Medicine. He was appointed Officer of the Order of the British Empire (OBE) in 2008 for services to medicine.

Professor Thomas is a Consultant Physician at the Newcastle Hospitals NHS Foundation Trust and Professor of Clinical Pharmacology and Therapeutics at Newcastle University, Director, National Poisons Information Service (Newcastle) Unit and the UK Teratology Information Service. 

Professor Thomas is a member of the Commission for Human Medicines and the Advisory Council on the Misuse of Drugs Technical Subcommittee. He is immediate Past President of the European Association of Poisons Centres and Clinical Toxicologists and chair of the National Poisons Information Service Clinical Standards Group.

He trained at St Thomas’s Hospital in London, the Freeman Hospital in Newcastle and at Newcastle University. His research interests include adverse drug reactions, especially drug-induced arrhythmia, poisoning and clinical toxicology. He has published extensively on ECG abnormalities, arrhythmias and sudden death associated with drug therapy, especially antipsychotic agents.